Search results for "statistical [Methods]"

showing 10 items of 1664 documents

The clinical use of statistical permutation test methodology: a tool for identifying predictive variables of outcome.

2015

<b><i>Objectives:</i></b> To identify the predictive variables affecting the outcome after radical surgery for bladder cancer by a newer statistical methodology, i.e. nonparametric combination (NPC). <b><i>Methods:</i></b> A multicenter study enrolled 1,312 patients who had undergone radical cystectomy for bladder cancer in 11 Italian oncological centers from January 1982 to December 2002. A statistical analysis<b> </b>of their medical history and diagnostic, pathological and postoperative variables was performed using a NPC test. The<b> </b>patients were included in a comprehensive database with medical history and cli…

AdultMalemedicine.medical_specialtyUrologyStatistics as TopicHydronephrosisnonparametric combinationCystectomyOutcome (game theory)Statistics NonparametricBladder cancer; Permutation test; PrognosisSettore MED/24 - UrologiaBladder cancer Prognosis Permutation testPredictive Value of TestsResamplingMedicineHumansPermutation testRadical surgeryIntensive care medicineAgedNeoplasm StagingRetrospective StudiesAged 80 and overCarcinoma Transitional CellBladder cancerbusiness.industryBladder cancerProstatePermutation testsMiddle Agedmedicine.diseasePrognosisradical surgery for bladder; nonparametric combinationradical surgery for bladderSurgeryPatient Outcome Assessmentbladder cancer; Prognosis; Permutation testsItalyUrinary Bladder NeoplasmsBladdder Cancer Cystectomy outcome statistical methodologyData Interpretation StatisticalLymphatic MetastasisMultivariate AnalysisFemalePredictive variablesradical surgery for bladder nonparametric combinationbusiness
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Erythrocyte deformability in morbid obesity before bariatric surgery. Influence of abdominal obesity.

2010

Although there are several studies dealing with erythrocyte deformability (ED) in obese patients, research on this topic in morbidly obese subjects is scarce. In these studies ED seems to be decreased, although the cause remains unknown. A case-control study in 76 morbid obese subjects (23 women and 53 men, aged 44 ± 13 years) and in 79 normal-weight controls (30 women and 49 men, aged 43 ± 13 years) was undertaken. ED has been determined by ektacytometric techniques in a Rheodyn SSD, by means of the elongation index (EI) at 12, 30 and 60 Pascals, along with anthropometric, lipidic, metabolic and inflammatory parameters. EI was statistically lower in morbidly obese subjects than in controls…

AdultMalemedicine.medical_specialtyWaistPhysiologyBariatric SurgeryInsulin resistancePhysiology (medical)Internal medicineStatistical significanceErythrocyte DeformabilitymedicineErythrocyte deformabilityHumansAbdominal obesitybusiness.industryHematologyAnthropometryMiddle Agedmedicine.diseaseObesitySurgeryObesity MorbidEndocrinologyCase-Control StudiesObesity AbdominalFemalemedicine.symptomInsulin ResistanceWaist CircumferenceCardiology and Cardiovascular MedicinebusinessBody mass indexClinical hemorheology and microcirculation
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Effects of different accentuated eccentric loads on acute neuromuscular, growth hormone, and blood lactate responses during a hypertrophic protocol.

2009

This study monitored acute neuromuscular responses and growth hormone (GH) and blood lactate (La) concentrations in the eccentric-concentric (ECC-CON) hypertrophic protocol by using various dynamic accentuated external resistance (DAER) loads in the bench press exercise. Male subjects (age = 32 +/- 4 years; n = 11) performed 4 sets of 10 repetitions with 2 minutes of recovery between the sets. The loads were 70, 80, 90, and 100% of 1 repetition maximum (RM) for the ECC phase, whereas 70% RM was constantly used for the CON phase. Electromyographic activity (EMG), ECC, CON, and isometric (ISOM) forces, serum GH and blood La, were measured at pre- and postloading. Significant reductions occurr…

AdultMalemedicine.medical_specialtygenetic structuresDeltoid curvePhysical Therapy Sports Therapy and RehabilitationIsometric exerciseElectromyographyBench pressMuscle hypertrophyInternal medicineStatistical significanceIsometric ContractionmedicineEccentricHumansOrthopedics and Sports MedicineMuscle SkeletalAnalysis of Variancemedicine.diagnostic_testAnthropometrybusiness.industryElectromyographyResistance TrainingGeneral MedicineEndocrinologyGrowth HormoneCardiologyLactatesAnalysis of variancebusinessJournal of strength and conditioning research
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Removal of annexin V–positive sperm cells for intracytoplasmic sperm injection in ovum donation cycles does not improve reproductive outcome: a contr…

2014

Objective To determine the effect of removing presumptive apoptotic sperm cells from samples from unselected males by means of magnetic activated cell sorting (MACS) on live-birth delivery rates after intracytoplasmic sperm injection (ICSI) in couples undergoing ovum donation (OD). Design Prospective, randomized, triple-blinded, and controlled study. Setting Private university-affiliated IVF center. Patient(s) A total of 237 infertile couples undergoing ICSI as part of an OD program. Intervention(s) Semen specimens from the control group were prepared by swim-up. Samples from the study group were prepared by swim-up followed by MACS and incubation with annexin V–conjugated microbeads to rem…

AdultMalemedicine.medical_specialtymedicine.medical_treatmentApoptosisSemenCell SeparationFertilization in VitroPhosphatidylserinesBiologyIntracytoplasmic sperm injectionlaw.inventionAndrologyMagneticsHuman fertilizationRandomized controlled trialPregnancylawStatistical significancemedicineHumansSperm Injections IntracytoplasmicAnnexin A5Birth RateGynecologyPregnancyOocyte DonationObstetrics and Gynecologymedicine.diseaseSpermatozoaSpermConfidence intervalSperm MaturationReproductive MedicineFemaleFertility and Sterility
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Influencing factors and predictors of early improvement in the acute treatment of schizophrenia and schizophrenia spectrum disorder.

2011

Abstract Background To examine the influencing factors and predictors of early improvement in schizophrenia patients. Methods 370 patients suffering from a schizophrenia spectrum disorder were examined within a naturalistic multicenter study. Early improvement was defined as a ≥30% PANSS total score reduction within the first two treatment weeks, response as a ≥50% improvement of the PANSS total score from admission to discharge and remission according to the consensus remission criteria. Baseline and course-related variables such as positive, negative and depressive symptoms, side effects, functioning and subjective well-being were examined regarding their explanatory value for early impro…

AdultMalemedicine.medical_specialtymedicine.medical_treatmentMedizinAntipsychotic treatment03 medical and health sciencesYoung Adult0302 clinical medicineRemission criteriaPredictive Value of TestsInternal medicinemedicineHumansPsychiatryAntipsychoticBiological PsychiatryDepressive symptomsRetrospective StudiesPsychiatric Status Rating Scalesbusiness.industryMiddle Agedmedicine.disease030227 psychiatry3. Good healthDiagnostic and Statistical Manual of Mental DisordersPsychiatry and Mental healthTreatment OutcomeMulticenter studyROC CurveSchizophreniaSchizophreniaFemalebusiness030217 neurology & neurosurgerySchizophrenia spectrumAntipsychotic AgentsFollow-Up StudiesJournal of psychiatric research
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Corpus callosum area in patients with bipolar disorder with and without psychotic features: an international multicentre study

2015

Background Previous studies have reported MRI abnormalities of the corpus callosum (CC) in patients with bipolar disorder (BD), although only a few studies have directly compared callosal areas in psychotic versus nonpsychotic patients with this disorder. We sought to compare regional callosal areas in a large international multicentre sample of patients with BD and healthy controls. Methods We analyzed anatomic T-1 MRI data of patients with BD-I and healthy controls recruited from 4 sites (France, Germany, Ireland and the United States). We obtained the mid-sagittal areas of 7 CC subregions using an automatic CC delineation. Differences in regional callosal areas between patients and contr…

AdultMaleoasis brain databasePediatricsmedicine.medical_specialtyBipolar DisorderNeuroimagingshapeLithiumCorpus callosumearly alzheimers-diseasesizeCorpus CallosumGermanyImage Processing Computer-AssistedmedicineHumansPharmacology (medical)In patientBipolar disorderPsychiatryCognitive impairmentmriBiological Psychiatrycognitive impairmentreliabilitymedicine.diagnostic_testExtramuralbusiness.industryMagnetic resonance imagingMiddle Agedmedicine.diseaseMagnetic Resonance ImagingWhite MatterUnited States3. Good healthDiagnostic and Statistical Manual of Mental DisordersPsychiatry and Mental healthMulticenter studyLinear ModelsFemaleabnormalitiesFrancei disorderbusinessrating-scaleIrelandResearch PaperAntipsychotic AgentsJournal of Psychiatry and Neuroscience
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Sexual Compulsivity and Sexual Sensation Seeking: A Preliminary Approach Among Male Sex Workers Compared to Gay Men in Spain

2015

This study aims to explore sexual compulsivity (SC) and sexual sensation seeking (SSS) in male sex workers (MSWs) compared to a group of non-MSW gay men. A total of 60 MSWs and 63 gay men answered the SC Scale and the SSS Scale. The total scales' mean score was slightly higher in the MSW population. Still, statistical differences were observed in only two SSS items. In spite of the absence of statistical significance, MSWs presented more sexual behavior interferences on their lives and higher failure to control sexual impulses. Future interventions among MSWs should focus on sexual self-control and impulsivity.

AdultMalesexual compulsivity050103 clinical psychologyPopulationSensationPsychological interventionSex workersImpulsivityRisk AssessmentDevelopmental psychologyYoung Adult03 medical and health sciencesSexual compulsivityRisk-Takingmale sex workersStatistical significancemedicineHumanssexual sensation seekingSensation seeking0501 psychology and cognitive sciencesHomosexuality Maleeducationgay meneducation.field_of_studySex Workers030505 public healthSocial Identification05 social sciencesClinical PsychologySexual behaviorSpainCompulsive Behaviormedicine.symptom0305 other medical sciencePsychologyClinical psychologyJournal of Sex & Marital Therapy
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Training at maximal power in resisted sprinting: Optimal load determination methodology and pilot results in team sport athletes.

2018

Aims: In the current study we investigated the effects of resisted sprint training on sprinting performance and underlying mechanical parameters (force-velocity-power profile) based on two different training protocols: (i) loads that represented maximum power output (Lopt) and a 50% decrease in maximum unresisted sprinting velocity and (ii) lighter loads that represented a 10% decrease in maximum unresisted sprinting velocity, as drawn from previous research (L10). Methods: Soccer [n = 15 male] and rugby [n = 21; 9 male and 12 female] club-level athletes were individually assessed for horizontal force-velocity and load-velocity profiles using a battery of resisted sprints, sled or robotic r…

AdultMalevelocityhuman performancePhysiology[SDV]Life Sciences [q-bio]educationlcsh:MedicinePilot ProjectsAthletic PerformanceResearch and Analysis MethodsRemote SensingWeight-BearingMotionMathematical and Statistical TechniquesMedicine and Health SciencesrunningHumansStatistical Methodslcsh:ScienceroboticsBehaviorBiological LocomotionPhysicsMechanical Engineeringlcsh:RBiology and Life SciencesClassical MechanicsResistance TrainingaccelerationSports ScienceAthletesPhysical Scienceslinear regression analysisRecreationRegression AnalysisEngineering and TechnologyFemalelcsh:Qsportshuman activitiesMathematicsStatistics (Mathematics)Research ArticleradarPLoS ONE
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Time-Varying Surrogate Data to Assess Nonlinearity in Nonstationary Time Series: Application to Heart Rate Variability

2009

We propose a method to extend to time-varying (TV) systems the procedure for generating typical surrogate time series, in order to test the presence of nonlinear dynamics in potentially nonstationary signals. The method is based on fitting a TV autoregressive (AR) model to the original series and then regressing the model coefficients with random replacements of the model residuals to generate TV AR surrogate series. The proposed surrogate series were used in combination with a TV sample entropy (SE) discriminating statistic to assess nonlinearity in both simulated and experimental time series, in comparison with traditional time-invariant (TIV) surrogates combined with the TIV SE discrimin…

AdultTime FactorsComputer scienceRestBiomedical EngineeringSurrogate dataHeart RateStatisticsHumansHeart rate variabilityEntropy (information theory)Computer SimulationNonstationarityEntropy (energy dispersal)Time seriesEntropy (arrow of time)StatisticModels StatisticalEntropy (statistical thermodynamics)RespirationNonlinear dynamicModels CardiovascularComplexitySample entropyNonlinear systemNonlinear DynamicsAutoregressive modelSettore ING-INF/06 - Bioingegneria Elettronica E InformaticaSurrogate dataTime-varying (TV) autoregressive (AR) modelHeart rate variability (HRV)AlgorithmsEntropy (order and disorder)IEEE Transactions on Biomedical Engineering
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Monocular versus binocular pupillometry.

2004

Purpose To quantify differences between monocular and binocular pupil size measurement under scotopic and mesopic conditions. Setting Department of Ophthalmology, Johannes Gutenberg-University, and Department of Medical Biometry, Epidemiology and Informatics, University of Mainz, Mainz, Germany. Methods Computerized dynamic pupillometry (P2000 SA, Procyon Instruments Ltd.) was used at 3 illumination levels: scotopic at 0.03 lux, mesopic low at 0.82 lux, and mesopic high at 6.4 lux. One hundred forty eyes of 70 healthy volunteers without ocular pathology were examined. The subjects were divided into 2 groups. In the first group, the pupil diameter was measured binocularly first. In the secon…

Adultgenetic structuresAdolescentMesopic visionmedicine.medical_treatmentDark AdaptationDiagnostic Techniques OphthalmologicalVision MonocularStatistical significanceRefractive surgeryMedicineHumansScotopic visionVision BinocularMonocularbusiness.industryPupileye diseasesSensory SystemsOphthalmologyQuartileOptometrySurgerysense organsbusinessBinocular visionPupillometryJournal of cataract and refractive surgery
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